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PI:
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Drs. Rebecca Nelson and Margaret
Smith |
Contact Details
334 Plant Science Bldg, Cornell University, Ithaca,
NY 14853
Phone: 1 607 254 7475
Email:
RJN7@cornell.edu
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Grantee:
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Cornell University/KARI |
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Grant No:
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2003 FS 041 |
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Amount:
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US $150,000 |
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Duration
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Three Years |
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Collaborators: Jedidah
Danson and Jane Ininda: Kenya Agriculture Research Institute Randy
Wisser, Ying Wei and Steve Kresovich: Cornell University
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Genomic regions
most consistently associated with disease resistance
identified based on an analysis of published QTL studies
in maize, as well as comparative analysis with resistance
studies in rice.
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Simple-sequence
repeat (SSR, or microsatellite) markers associated with
putative disease QTL regions, and also those providing
general genome coverage, selected and provided to KARI for
use in analysis of potential donors of resistance.
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Near-isogenic lines (QTL-NILs)
are being developed for selected resistance donors, to
allow the QTL regions to be more precisely defined and
characterized.
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Positional candidate
genes (genes related to plant defense and likely located
at the QTL) are being identified through comparative
analysis with the sequenced rice genome.
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SSR and candidate
gene markers are being used for analysis of maize
populations developed by CIMMYT through recurrent
selection for disease resistance, to identify regions
showing shifts in allele frequency and to identify the
specific alleles enriched through selection for disease
resistance.
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An approach to
testing the phenotypic effects of individual disease QTL
alleles is being developed for segregating inbred and F2
populations.
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Collaborative
interaction and technical support is provided to the KARI
maize improvement program through visits, telephone
conferences and exchange of research materials.
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