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PI:
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Zeyaur Khan and Ahmed Hassanali
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Contact details
Dr.
Zeyaur Khan
ICIPE
P.
O. Box 30772, Nairobi, Kenya
Phone:
+254 (2) 861680-4
Fax:
254 2 860110
Email
direct from site:
zkhan@icipe.org
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Grantee:
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ICIPE
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Amount:
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US $75,000
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Duration:
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Three
Years
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Project
Outputs
Publication: Z. R.
Khan, A. Hassanali, W. Overholt, T. M. Khamis, A. M. Hooper, J. A.
Pickett, L. J. Wadhams, C. M. Woodcock. 2002. Control of the
witchweed Striga hermonthica
by intercropping with Desmodium
uncinatum spp. and the mechanism defined as allelopathic. J.
Chem. Ecol. 28:1871-1885.
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A group of
structurally related isoflavanoid compounds have been isolated from
this allelopathic root exudate by bioassay-guided HPLC and their
structure elucidated by Microprobe-NMR analysis.
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The
biological activity of some components of the root exudate stimulate
germination (e.g. uncinanone B, 1),
while the biological activity of other components inhibit the length
of the radical after germination (e.g. uncinanone C, 2).
This is the first example of a newly identified, potential
allelopathic mechanism to prevent S.
hermonthica parasitism.
Publication:
Muniru K. Tsanuo, Ahmed Hassanali, Antony M. Hooper, Zeyaur Khan, Festus
Kaberia, John A. Pickett, Lester J. Wadhams. 2003. Isoflavanones From
The Allelopathic Aqueous Root Exudate Of Desmodium
uncinatum. Phytochemistry (accepted).
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Polar
fractions from the allelopathic root exudate are the most potent
inhibitors of radical length. A
number of compounds have been isolated from these fractions by HPLC
purification. Structure
elucidation is now in progress.
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Desmodium intortum shows greater drought tolerance than D.
uncinatum and has been used successfully in the field to control
striga in sorghum. Even
in the first season of protection, yields were over 2.2 tonne/ha
compared with ca 0.8
tonne/ha for control.
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